DNA Replication Simulator

In this interactive Biology activity, you’ll connect concepts like DNA replication, Okazaki fragments, leading strand, and lagging strand.

Take charge of DNA copying. Use enzyme tools in the right order, unwind the helix, unzip the strands, lay down primers, add nucleotides, and seal the gaps to build a matching strand. Drag nucleotides from the free pool, compare leading and lagging strands, and tweak conditions like temperature and pH to see how they change success.

Key Features:
– Hands‑on enzyme toolkit: Topoisomerase, Helicase, Primase, Polymerase, Ligase
– Drag‑and‑drop nucleotides to build new strands
– See the difference between leading and lagging strands (Okazaki fragments)
– Adjustable temperature and pH to explore “best” vs “worst” conditions
– A large, easy‑to‑follow DNA view to make every step clear

Educational Resources

Student Handouts

AP/College Student Handout Download PDF
High School Student Handout Download PDF
Middle School Student Handout Download PDF

Teacher Guides

AP/College Teacher Guide Download PDF
High School Teacher Guide Download PDF
Middle School Teacher Guide Download PDF