Objective: Learn how genetic information flows from DNA to proteins.
Step-by-Step Guide:
Generate DNA: Click "Generate New DNA" to create a random DNA sequence with exons (coding) and introns (non-coding).
Add Promoter: Select the Promoter card and execute - this is required before transcription can begin.
Transcribe: Use RNA Polymerase to create RNA copies. Add Transcription Factor for increased efficiency!
Process RNA: Use Spliceosome to remove introns and create mature mRNA.
Add Modifications: Apply 5' Cap and Poly-A Tail to protect and stabilize the mRNA.
Translate: Use both tRNA and rRNA together to translate mRNA into proteins.
Experiment: Try mutations and alternative splicing to see how they affect the final protein!
Gene Editing: Use CRISPR to precisely edit DNA sequences by changing specific codons!
Color Code:
A (Adenine) •
T (Thymine) •
C (Cytosine) •
G (Guanine) •
U (Uracil in RNA)
Learning Objectives
Complete these objectives to master the Central Dogma!
Cause a Random Mutation
Use the Mutagen tool to introduce a random point mutation in your DNA sequence.
Simulate Transcription
Activate a Promoter and use RNA Polymerase to transcribe DNA into pre-mRNA.
Simulate RNA Processing
Use the Spliceosome to remove introns and add a 5' Cap and Poly-A Tail to create mature mRNA.
Simulate Translation
Use tRNA and rRNA together to translate mature mRNA into a polypeptide chain.
Modify DNA Using CRISPR
Use the CRISPR tool to make precise edits to your DNA nucleotide sequence.
0 / 5 Objectives Completed
🧬 CRISPR Gene Editor
Instructions: Edit the DNA sequence below. Each line represents a gene segment.
Use only the letters A, T, C, G. Separate codons with spaces for readability.
Welcome to Epic Genetics! Click Tutorial for help.