PEEBEDU
Identify a substrate with a shape compatible with the active site.
ACTIVE SITE READY00 / 3 reactions
INTEGRITY100%
MOVEMENT SPEED0
TEMPERATURE 20.0°CBELOW OPTIMAL
20°COPTIMAL 25–30°C46°C OVERHEAT
Cooling happens automatically when heating stops
No inhibitor bound · active site available
ACTIVE-SITE VIEW
PEEBEDU
LEVEL 01 / SUBSTRATE RECOGNITIONLEVEL 02 / SUBSTRATE CONCENTRATION

Control an enzyme.

60 SEC
OBSERVATION

You control an enzyme in the cytoplasm. Enzymes are biological catalysts. Move toward a compatible substrate to form an enzyme–substrate complex at the active site.

ENZYME A / BINDING PROFILEVIEW 01
A substrate fits the glowing active site.The shape of the green substrate is complementary to the active site highlighted in cyan on the blue enzyme. The arrows end on the corresponding curved surfaces. SubstrateMatching edgeActive siteEnzyme
PRIMARY OBJECTIVE03

Catalyze three reactions.

Bind substrates with shapes compatible with the active site. The enzyme catalyzes their conversion into products.

Enzymes catalyze reactions by lowering activation energy.
OPTIMAL pH6.5—7.5
OPTIMAL TEMPERATURE25—30°C
ENZYME SHAPEStay near the optimal ranges.Binding requires pH 6.5–7.5. Extreme pH or heat changes the active site.

IDENTIFY BEFORE CONTACTRed inhibitors block the active site. Green does not mean safe: some green molecules also inhibit the enzyme. Read the label in the circle before making contact.

Identify molecules Tap to view / close
GREEN / MATCH

Substrate

Its shape and charge match the active site. Binding forms an enzyme–substrate complex.

RED / INHIBITOR

Competitive inhibitor

It fits the active site but blocks substrates. The enzyme cannot react there until it leaves.

GREEN / MISMATCH

Non-substrate

Its shape does not fit. Your enzyme cannot turn it into a product.

GREEN / ALLOSTERIC SITE

Noncompetitive inhibitor

It binds at a different site, called the allosteric site. This changes the active site and slows the reaction.

Controls

Move. Your enzyme moves forward automatically. Use the arrow keys to steer. Use W / S to change speed and Q / E to rotate your enzyme.Touch and hold the scene in the direction you want to turn, or drag the left pad. Hold Speed + / − to change speed or Roll to rotate.

Bind. Stop steering with a substrate in the circle to follow it. After three seconds, your enzyme moves in for collision. Steer to release it.

Heat. Tap Heat to raise temperature. You can also hold T. Overheating distorts the active site.

Slow or pause. Hold Space to slow down. Press Esc to pause.Hold Brake to slow down. Tap Pause to stop the game.

Loading the cytoplasm…