IVF Simulator

Gene	Alleles	Genotype of Concern
HBB	A / a	aa → Sickle Cell Disease
HEXA	T / t	tt → Tay-Sachs Disease
CFTR	C / c	cc → Cystic Fibrosis

🧬 Sexual Reproduction & Gametes

Sexual reproduction involves the fusion of two specialized cells called gametes: the oocyte (egg) from the female and spermatozoon (sperm) from the male. When these haploid cells unite during fertilization, they form a diploid zygote containing genetic material from both parents.

🔬 Laboratory Technique: Position your cursor over embryos in the microscope field to view their complete genetic karyotype.

🔬 The IVF Process

Use the micropipette for gamete manipulation
Collect mature oocytes (female gametes)
Collect motile spermatozoa (male gametes)
Perform in vitro fertilization in the petri dish
Observe zygote formation and early embryonic development
Transfer viable embryos to culture medium for growth
Utilize cryopreservation for embryo storage

💡 Scientific Fact: In IVF, we bypass natural competition through intracytoplasmic sperm injection (ICSI), where a single sperm is directly injected into the oocyte.

🧬 Preimplantation Genetic Testing (PGT)

Genetic screening identifies chromosomal abnormalities and monogenic disorders:

Sickle Cell Disease - HBB gene (aa)
Tay-Sachs Disease - HEXA gene (tt)
Cystic Fibrosis - CFTR gene (cc)

Objective: Create two healthy embryos.

Activity Log

🏆 Challenge Progress

✨ IVF Simulator Lab ✨

🔬 What is IVF?

🎮 Controls

🧬 Genetic Markers

🏆 Challenge 🏆

Activity Log

🧬 Sexual Reproduction & Gametes

🔬 The IVF Process

🧬 Preimplantation Genetic Testing (PGT)

🏆 Challenge Progress